| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RDH11 (70-145) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RDH11 |
| Gene ID: |
51109 |
| Uniprot ID: |
RDH11_HUMAN |
| Immunogen Region: |
70-145 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 70-145 of human RDH11 (NP_057110.3). |
| Immunogen Sequence: |
LACRDVEKGELVAKEIQTTT GNQQVLVRKLDLSDTKSIRA FAKGFLAEEKHLHVLINNAG VMMCPYSKTADGFEMH |
| Tissue Specificity | Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. |
| Post Translational Modifications | Not glycosylated. |
| Function | Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol. Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal. Has no dehydrogenase activity towards steroid. |
| Protein Name | Retinol Dehydrogenase 11Androgen-Regulated Short-Chain Dehydrogenase/Reductase 1Hcv Core-Binding Protein Hcbp12Prostate Short-Chain Dehydrogenase/Reductase 1Retinal Reductase 1Ralr1Short Chain Dehydrogenase/Reductase Family 7c Member 1 |
| Database Links | Reactome: R-HSA-2453902Reactome: R-HSA-5365859Reactome: R-HSA-975634 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Retinol Dehydrogenase 11 antibodyAnti-Androgen-Regulated Short-Chain Dehydrogenase/Reductase 1 antibodyAnti-Hcv Core-Binding Protein Hcbp12 antibodyAnti-Prostate Short-Chain Dehydrogenase/Reductase 1 antibodyAnti-Retinal Reductase 1 antibodyAnti-Ralr1 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 7c Member 1 antibodyAnti-RDH11 antibodyAnti-ARSDR1 antibodyAnti-PSDR1 antibodyAnti-SDR7C1 antibodyAnti-CGI-82 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
