| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RCL1 |
| Gene ID: | 10171 |
| Uniprot ID: | RCL1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RCL1 (NP_005763.3). |
| Immunogen Sequence: | MATQAHSLSYAGCNFLRQRL VLSTLSGRPVKIRKIRARDD NPGLRDFEASFIRLLDKITN GSRIEINQTGTTLYYQPGLL YGGSVEHDCSVLRGIGYYLE SLLCLAPFMKHPLKIVLRGV TNDQVDPSVDVLKATALPLL KQFGIDGESFELKIVRRGMP PGGGGEVVFSCPVRKVLKPI QLTDPGKIKRIRGMAYSVRV SPQMANRIVDSARSILNKFI PDIYIYTDHMKGVNSGKSP |
| Function | As part of the small subunit (SSU) processome, it plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA. Activates BMS1 by promoting GDP/GTP exchange. Does not have cyclase activity. |
| Protein Name | Rna 3'-Terminal Phosphate Cyclase-Like Protein |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Rna 3'-Terminal Phosphate Cyclase-Like Protein antibodyAnti-RCL1 antibodyAnti-RNAC antibodyAnti-RPC2 antibodyAnti-RPCL1 antibodyAnti-RTC2 antibodyAnti-HSPC338 antibody |
Information sourced from Uniprot.org
