Anti-RBM5 antibody (226-275 aa) (STJ93969)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RBM5 at the amino acid range 226-275
General Information
| Short Description | Rabbit polyclonal anti-RNA-binding protein 5 (226-275 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RBM5 |
| Gene ID | 10181 |
| Uniprot ID | RBM5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RBM5 at the amino acid range 226-275 |
| Immunogen Region | 226-275 aa |
| Specificity | LUCA15 Polyclonal Antibody detects endogenous levels of LUCA15 protein. |
Additional Info
| Function | Component of the spliceosome A complex. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. |
| Protein Name | Rna-Binding Protein 5Protein G15Putative Tumor Suppressor Luca15Rna-Binding Motif Protein 5Renal Carcinoma Antigen Ny-Ren-9 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein 5 antibodyAnti-Protein G15 antibodyAnti-Putative Tumor Suppressor Luca15 antibodyAnti-Rna-Binding Motif Protein 5 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-9 antibodyAnti-RBM5 antibodyAnti-H37 antibodyAnti-LUCA15 antibody |
Information sourced from Uniprot.org