• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using RBM5 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HUVEC cells, using RBM5 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using LUCA15 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-RBM5 antibody (226-275 aa) (STJ93969)

SKU:
STJ93969

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNA-binding protein 5 (226-275 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RBM5
Gene ID: 10181
Uniprot ID: RBM5_HUMAN
Immunogen Region: 226-275 aa
Specificity: LUCA15 Polyclonal Antibody detects endogenous levels of LUCA15 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RBM5 at the amino acid range 226-275
Function Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Protein Name Rna-Binding Protein 5
Protein G15
Putative Tumor Suppressor Luca15
Rna-Binding Motif Protein 5
Renal Carcinoma Antigen Ny-Ren-9
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Rna-Binding Protein 5 antibody
Anti-Protein G15 antibody
Anti-Putative Tumor Suppressor Luca15 antibody
Anti-Rna-Binding Motif Protein 5 antibody
Anti-Renal Carcinoma Antigen Ny-Ren-9 antibody
Anti-RBM5 antibody
Anti-H37 antibody
Anti-LUCA15 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance