| Tissue Specificity | Highly expressed in placenta, liver, skeletal muscle, heart and kidney. Expressed at lower levels in the colon, thymus, spleen, small intestine and lung. |
| Post Translational Modifications | Aryl sulfonamide anticancer drugs, such as indisulam (E7070) or E7820, promote ubiquitination and subsequent degradation by the DCX(DCAF15) complex. Aryl sulfonamide anticancer drugs change the substrate specificity of DCAF15 by acting as a molecular glue that promotes binding between DCAF15 and weak affinity interactor RBM23. |
| Function | RNA-binding protein that acts both as a transcription coactivator and pre-mRNA splicing factor. Regulates steroid hormone receptor-mediated transcription, independently of the pre-mRNA splicing factor activity. |
| Protein Name | Probable Rna-Binding Protein 23Caper BetaCaperbetaRna-Binding Motif Protein 23Rna-Binding Region-Containing Protein 4Splicing Factor Sf2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Probable Rna-Binding Protein 23 antibodyAnti-Caper Beta antibodyAnti-Caperbeta antibodyAnti-Rna-Binding Motif Protein 23 antibodyAnti-Rna-Binding Region-Containing Protein 4 antibodyAnti-Splicing Factor Sf2 antibodyAnti-RBM23 antibodyAnti-RNPC4 antibodyAnti-PP239 antibody |
Information sourced from Uniprot.org
