Anti-RASSF2 antibody [R06-2H4] (STJA0034801)

SKU:
STJA0034801
£133.50 - £281.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-RASSF2 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R06-2H4
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: RASSF2
Gene ID: 9770
Uniprot ID: RASF2_HUMAN
Immunogen: A synthetic peptide of human RASSF2
Tissue Specificity Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Post Translational Modifications Phosphorylated by STK3/MST2 and STK4/MST1.
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Protein Name Ras Association Domain-Containing Protein 2
Database Links
Cellular Localisation Nucleus
Cytoplasm
Chromosome
Centromere
Kinetochore
Translocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1
Alternative Antibody Names Anti-Ras Association Domain-Containing Protein 2 antibody
Anti-RASSF2 antibody
Anti-CENP-34 antibody
Anti-KIAA0168 antibody

Information sourced from Uniprot.org