| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-RASSF2 (N-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.IHC: Paraffin embedded Human Spleen, Thymus and Liver. Recommended concentration: 3.75µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RASSF2 |
| Gene ID: | 9770 |
| Uniprot ID: | RASF2_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_055552.1; NP_739580.1 |
| Immunogen Sequence: | PCGQDKYISKNE |
| Post Translational Modifications | Phosphorylated by STK3/MST2 and STK4/MST1. |
| Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
| Protein Name | Ras Association Domain-Containing Protein 2 |
| Cellular Localisation | NucleusCytoplasmChromosomeCentromereKinetochoreTranslocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1 |
| Alternative Antibody Names | Anti-Ras Association Domain-Containing Protein 2 antibodyAnti-RASSF2 antibodyAnti-CENP-34 antibodyAnti-KIAA0168 antibody |
Information sourced from Uniprot.org