Anti-RASSF2 antibody (109-158 aa) (STJ95376)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RASSF2 at the amino acid range 109-158
General Information
| Short Description | Rabbit polyclonal anti-Ras association domain-containing protein 2 (109-158 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RASSF2 |
| Gene ID | 9770 |
| Uniprot ID | RASF2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RASSF2 at the amino acid range 109-158 |
| Immunogen Region | 109-158 aa |
| Specificity | RASSF2 Polyclonal Antibody detects endogenous levels of RASSF2 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by STK3/MST2 and STK4/MST1. |
| Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
| Protein Name | Ras Association Domain-Containing Protein 2 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmChromosomeCentromereKinetochoreTranslocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1 |
| Alternative Antibody Names | Anti-Ras Association Domain-Containing Protein 2 antibodyAnti-RASSF2 antibodyAnti-CENP-34 antibodyAnti-KIAA0168 antibody |
Information sourced from Uniprot.org