| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Rap guanine nucleotide exchange factor 6 (460-540 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAPGEF6 |
| Gene ID: | 51735 |
| Uniprot ID: | RPGF6_HUMAN |
| Immunogen Region: | 460-540 aa |
| Specificity: | RPGF6 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 460-540 |
| Function | Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. |
| Protein Name | Rap Guanine Nucleotide Exchange Factor 6Pdz Domain-Containing Guanine Nucleotide Exchange Factor 2Pdz-Gef2Ra-Gef-2 |
| Cellular Localisation | CytoplasmCell MembraneUpon Binding To M-RasIt Translocates To The Plasma Membrane |
| Alternative Antibody Names | Anti-Rap Guanine Nucleotide Exchange Factor 6 antibodyAnti-Pdz Domain-Containing Guanine Nucleotide Exchange Factor 2 antibodyAnti-Pdz-Gef2 antibodyAnti-Ra-Gef-2 antibodyAnti-RAPGEF6 antibodyAnti-PDZGEF2 antibody |
Information sourced from Uniprot.org