| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Ramp1-Mouse (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:64000.WB: Experiments gave bands at approx. 18kDa and 40kDa in Rat Brain lysate after 0.3µg/ml antibody staining. The appearance of a band with much higher molecular weight corresponds to earlie |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
RAMP1 |
| Gene ID: |
10267 |
| Uniprot ID: |
RAMP1_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_058590.1; NP_848488.2 |
| Specificity: |
This antibody is expected to recognize isoform 1 (NP_058590.1) only. |
| Immunogen Sequence: |
DYQSKRTEGIV |
| Function | Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA. |
| Protein Name | Receptor Activity-Modifying Protein 1Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1Crlr Activity-Modifying Protein 1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Receptor Activity-Modifying Protein 1 antibodyAnti-Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1 antibodyAnti-Crlr Activity-Modifying Protein 1 antibodyAnti-RAMP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
