Anti-RAMP1 antibody (104-117) (STJ28530)

SKU:
STJ28530
£112.50 - £524.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:100-1:500
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAMP1
Gene ID: 10267
Uniprot ID: RAMP1_HUMAN
Immunogen Region: 104-117
Specificity: A synthetic peptide corresponding to a sequence within amino acids 21-120 of human RAMP1 (NP_005846.1).
Immunogen Sequence: LFMTTACQEANYGALLRELC LTQFQVDMEAVGETLWCDWG RTIRSYRELADCTWHMAEKL GCFWPNAEVDRFFLAVHGRY FRSCPISGRAVRDPPGSILY PFIVVPITVTLLVTALVVWQ
Tissue Specificity Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.
Function Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA.
Protein Name Receptor Activity-Modifying Protein 1
Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1
Crlr Activity-Modifying Protein 1
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Receptor Activity-Modifying Protein 1 antibody
Anti-Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1 antibody
Anti-Crlr Activity-Modifying Protein 1 antibody
Anti-RAMP1 antibody

Information sourced from Uniprot.org