| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAMP1 |
| Gene ID: |
10267 |
| Uniprot ID: |
RAMP1_HUMAN |
| Immunogen Region: |
104-117 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 21-120 of human RAMP1 (NP_005846.1). |
| Immunogen Sequence: |
LFMTTACQEANYGALLRELC LTQFQVDMEAVGETLWCDWG RTIRSYRELADCTWHMAEKL GCFWPNAEVDRFFLAVHGRY FRSCPISGRAVRDPPGSILY PFIVVPITVTLLVTALVVWQ |
| Tissue Specificity | Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract. |
| Function | Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA. |
| Protein Name | Receptor Activity-Modifying Protein 1Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1Crlr Activity-Modifying Protein 1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Receptor Activity-Modifying Protein 1 antibodyAnti-Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1 antibodyAnti-Crlr Activity-Modifying Protein 1 antibodyAnti-RAMP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
