Anti-RABGEF1 antibody (291-341 aa) (STJ194178)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human RABX5 at the amino acid range 291-341
General Information
| Short Description | Rabbit polyclonal anti-Rab5 GDP/GTP exchange factor (291-341 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RABGEF1 |
| Gene ID | 27342 |
| Uniprot ID | RABX5_HUMAN |
| Immunogen | Synthesized peptide derived from the human RABX5 at the amino acid range 291-341 |
| Immunogen Region | 291-341 aa |
| Specificity | This antibody detects endogenous levels of RABX5 at Human/Mouse |
Additional Info
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. |
| Protein Name | Rab5 Gdp/Gtp Exchange FactorRap1Rabaptin-5-Associated Exchange Factor For Rab5Rabex-5 |
| Database Links | Reactome: R-HSA-8854214Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling Endosome |
| Alternative Antibody Names | Anti-Rab5 Gdp/Gtp Exchange Factor antibodyAnti-Rap1 antibodyAnti-Rabaptin-5-Associated Exchange Factor For Rab5 antibodyAnti-Rabex-5 antibodyAnti-RABGEF1 antibodyAnti-RABEX5 antibody |
Information sourced from Uniprot.org