| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Rab5 GDP/GTP exchange factor (291-341 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RABGEF1 |
| Gene ID: | 27342 |
| Uniprot ID: | RABX5_HUMAN |
| Immunogen Region: | 291-341 aa |
| Specificity: | This antibody detects endogenous levels of RABX5 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human RABX5 at the amino acid range 291-341 |
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. |
| Protein Name | Rab5 Gdp/Gtp Exchange FactorRap1Rabaptin-5-Associated Exchange Factor For Rab5Rabex-5 |
| Database Links | Reactome: R-HSA-8854214Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling Endosome |
| Alternative Antibody Names | Anti-Rab5 Gdp/Gtp Exchange Factor antibodyAnti-Rap1 antibodyAnti-Rabaptin-5-Associated Exchange Factor For Rab5 antibodyAnti-Rabex-5 antibodyAnti-RABGEF1 antibodyAnti-RABEX5 antibody |
Information sourced from Uniprot.org