Anti-RABEP1 antibody (549-598 aa) (STJ95312)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RABEP1 at the amino acid range 549-598
General Information
| Short Description | Rabbit polyclonal anti-Rab GTPase-binding effector protein 1 (549-598 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RABEP1 |
| Gene ID | 9135 |
| Uniprot ID | RABE1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RABEP1 at the amino acid range 549-598 |
| Immunogen Region | 549-598 aa |
| Specificity | Rabaptin-5 Alpha Polyclonal Antibody detects endogenous levels of Rabaptin-5 Alpha protein. |
Additional Info
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium. |
| Protein Name | Rab Gtpase-Binding Effector Protein 1Rabaptin-4Rabaptin-5Rabaptin-5alphaRenal Carcinoma Antigen Ny-Ren-17 |
| Database Links | Reactome: R-HSA-8854214 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling EndosomeCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Rab Gtpase-Binding Effector Protein 1 antibodyAnti-Rabaptin-4 antibodyAnti-Rabaptin-5 antibodyAnti-Rabaptin-5alpha antibodyAnti-Renal Carcinoma Antigen Ny-Ren-17 antibodyAnti-RABEP1 antibodyAnti-RAB5EP antibodyAnti-RABPT5 antibodyAnti-RABPT5A antibody |
Information sourced from Uniprot.org