| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Rab GTPase-binding effector protein 1 (549-598 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RABEP1 |
| Gene ID: | 9135 |
| Uniprot ID: | RABE1_HUMAN |
| Immunogen Region: | 549-598 aa |
| Specificity: | Rabaptin-5 Alpha Polyclonal Antibody detects endogenous levels of Rabaptin-5 Alpha protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RABEP1 at the amino acid range 549-598 |
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium. |
| Protein Name | Rab Gtpase-Binding Effector Protein 1 Rabaptin-4 Rabaptin-5 Rabaptin-5alpha Renal Carcinoma Antigen Ny-Ren-17 |
| Database Links | Reactome: R-HSA-8854214 |
| Cellular Localisation | Cytoplasm Early Endosome Recycling Endosome Cytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Rab Gtpase-Binding Effector Protein 1 antibody Anti-Rabaptin-4 antibody Anti-Rabaptin-5 antibody Anti-Rabaptin-5alpha antibody Anti-Renal Carcinoma Antigen Ny-Ren-17 antibody Anti-RABEP1 antibody Anti-RAB5EP antibody Anti-RABPT5 antibody Anti-RABPT5A antibody |
Information sourced from Uniprot.org