| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Rab GTPase-binding effector protein 1 (549-598 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RABEP1 |
| Gene ID: |
9135 |
| Uniprot ID: |
RABE1_HUMAN |
| Immunogen Region: |
549-598 aa |
| Specificity: |
Rabaptin-5 Alpha Polyclonal Antibody detects endogenous levels of Rabaptin-5 Alpha protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human RABEP1 at the amino acid range 549-598 |
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium. |
| Protein Name | Rab Gtpase-Binding Effector Protein 1Rabaptin-4Rabaptin-5Rabaptin-5alphaRenal Carcinoma Antigen Ny-Ren-17 |
| Database Links | Reactome: R-HSA-8854214 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling EndosomeCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Rab Gtpase-Binding Effector Protein 1 antibodyAnti-Rabaptin-4 antibodyAnti-Rabaptin-5 antibodyAnti-Rabaptin-5alpha antibodyAnti-Renal Carcinoma Antigen Ny-Ren-17 antibodyAnti-RABEP1 antibodyAnti-RAB5EP antibodyAnti-RABPT5 antibodyAnti-RABPT5A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
