| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ras-related protein Rab-41 (115-164 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB41 |
| Gene ID: | 347517 |
| Uniprot ID: | RAB41_HUMAN |
| Immunogen Region: | 115-164 aa |
| Specificity: | Rab 41 Polyclonal Antibody detects endogenous levels of Rab 41 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RAB41 at the amino acid range 115-164 |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB41 is required for normal Golgi ribbon organization and ER-to-Golgi trafficking. |
| Protein Name | Ras-Related Protein Rab-41 |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-8873719 |
| Cellular Localisation | CytoplasmPunctate Localization Concentrated In Ruffled Regions At The Cell Periphery |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-41 antibodyAnti-RAB41 antibody |
Information sourced from Uniprot.org
