Anti-Rab3D antibody [PT1476R] (STJA0040287)

SKU:
STJA0040287
$207.00 - $745.20
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Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Ras-Related Protein Rab-3d for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : PT1476R
Conjugation: Unconjugated
Isotype: IgGk
Formulation: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification: Protein A
Dilution Range: IHC 1:200-1:1000
WB 1:2000-1:10000
IF 1:200-1:1000
ELISA 1:5000-1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB3D
Gene ID: 9545
Uniprot ID: RAB3D_HUMAN
Specificity: Endogenous
Post Translational Modifications Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and CHML.
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes.
Protein Name Ras-Related Protein Rab-3d
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8873719
Cellular Localisation Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Alternative Antibody Names Anti-Ras-Related Protein Rab-3d antibody
Anti-RAB3D antibody
Anti-GOV antibody
Anti-RAB16 antibody

Information sourced from Uniprot.org