Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Monoclonal |
Clone ID: |
SRM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
RAB3C |
Gene ID: |
115827 |
Uniprot ID: |
RAB3C_HUMAN |
Immunogen Region: |
128-227 aa |
Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 128-227 of human RAB3C (NP_612462.1). |
Immunogen Sequence: |
IKTYSWDNAQVILVGNKCDM EDERVISTERGQHLGEQLGF EFFETSAKDNINVKQTFERL VDIICDKMSESLETDPAITA AKQNTRLKETPPPPQPNCAC |
Tissue Specificity | Expressed in brain, placenta and lung. |
Post Translational Modifications | Phosphorylation of Thr-94 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitor GDI2. |
Function | Protein transport. Probably involved in vesicular traffic. |
Protein Name | Ras-Related Protein Rab-3c |
Database Links | Reactome: R-HSA-8873719 |
Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
Alternative Antibody Names | Anti-Ras-Related Protein Rab-3c antibodyAnti-RAB3C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance