Anti-RAB26 antibody (180-256 aa) (STJ96440)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Rab 26 at the amino acid range 180-256
General Information
| Short Description | Rabbit polyclonal anti-Ras-related protein Rab-26 (180-256 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAB26 |
| Gene ID | 25837 |
| Uniprot ID | RAB26_HUMAN |
| Immunogen | Synthesized peptide derived from Rab 26 at the amino acid range 180-256 |
| Immunogen Region | 180-256 aa |
| Specificity | Rab 26 Polyclonal Antibody detects endogenous levels of Rab 26 protein. |
Additional Info
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB26 mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. |
| Protein Name | Ras-Related Protein Rab-26 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Golgi Apparatus MembraneLipid-AnchorCytoplasmic SideCytoplasmic VesicleSecretory Vesicle MembraneNot Localized At The Plasma MembraneInhibition Of S-Geranylgeranyl Cysteine Formation Abolishes Membrane Location |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-26 antibodyAnti-RAB26 antibody |
Information sourced from Uniprot.org