| Host: | Rabbit |
| Applications: | WB/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Rab22A for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R07-3A8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/mL |
| Dilution Range: | WB 1:500-1:1000IP 1:20 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | RAB22A |
| Gene ID: | 57403 |
| Uniprot ID: | RB22A_HUMAN |
| Immunogen: | A synthetic peptide of human RAB22A |
| Function | Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form. |
| Protein Name | Ras-Related Protein Rab-22aRab-22 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Endosome MembraneLipid-AnchorCell MembraneEarly EndosomeLate EndosomeCell ProjectionRuffleCytoplasmic VesiclePhagosomePhagosome MembraneCytoplasmic SideRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-22a antibodyAnti-Rab-22 antibodyAnti-RAB22A antibodyAnti-RAB22 antibody |
Information sourced from Uniprot.org
