| Host: |
Goat |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse/Monkey/Canine |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-RAB20, member RAS oncogene family (130aa C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: |
This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: |
2 mg/ml |
| Dilution Range: |
WB 1:250-1:2000 |
| Storage Instruction: |
Store at-20 C for long-term storage. Store at 2-8 C for up to one month. |
| Gene Symbol: |
RAB20 |
| Gene ID: |
55647 |
| Uniprot ID: |
RAB20_HUMAN |
| Immunogen Region: |
130aa C-Term |
| Accession Number: |
ENSG00000139832 |
| Specificity: |
Detects Rab20 in transfected cells with GFP-Rab20 by Western blot. Detects levels of endogenous Rab20 (testis, liver and kidney) by Western blot. |
| Immunogen: |
Purified recombinant peptide derived from within residues 130 aa to the C-terminus of Rab20 produced in E. coli. |
| Tissue Specificity | Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level). |
| Function | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. |
| Protein Name | Ras-Related Protein Rab-20 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesiclePhagosomePhagosome MembraneLipid-AnchorCytoplasmic SideHighly Enriched On Apical Endocytic Structures In Polarized Epithelial Cells Of Kidney Proximal TubulesRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-20 antibodyAnti-RAB20 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
