Function | Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation. |
Protein Name | Regulator Of G-Protein Signaling 9-Binding ProteinRgs9-Anchoring Protein |
Database Links | Reactome: R-HSA-2514859 |
Cellular Localisation | MembraneSingle-Pass Type Iv Membrane Protein |
Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 9-Binding Protein antibodyAnti-Rgs9-Anchoring Protein antibodyAnti-RGS9BP antibodyAnti-R9AP antibody |
Information sourced from Uniprot.org