Anti-PXK antibody (1-200) (STJ117653)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PXK (1-200) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PXK |
| Gene ID | 54899 |
| Uniprot ID | PXK_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MAFMEKPPAGKVLLDDTVPL TAAIEASQSLQSHTEYIIRV QRGISVENSWQIVRRYSDFD LLNNSLQIAGLSLPLPPKKL IGNMDREFIAERQKGLQNYL NVITTNHILSNCELVKKFLD PNNYSANYTEIALQQVSMFF RSEPKWEVVEPLKDIGWRIR KKYFLMKIKNQPKERLVLSW ADLGPDKYLSDKDFQCLIKL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PXK (NP_060241.2). |
Additional Info
| Tissue Specificity | Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated. |
| Function | Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. |
| Protein Name | Px Domain-Containing Protein Kinase-Like ProteinModulator Of Na -K-AtpaseMonaka |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinAlso Associates With The Plasma MembraneIsoform 3 Is Present Throughout The Cell |
| Alternative Antibody Names | Anti-Px Domain-Containing Protein Kinase-Like Protein antibodyAnti-Modulator Of Na -K-Atpase antibodyAnti-Monaka antibodyAnti-PXK antibody |
Information sourced from Uniprot.org