Anti-PUM3 antibody (STJA0008930)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PUF-A, KIAA0020
General Information
| Short Description | Rabbit polyclonal anti-Pumilio homolog 3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PUM3 |
| Gene ID | 9933 |
| Uniprot ID | PUM3_HUMAN |
| Immunogen | Synthesized peptide derived from human PUF-A, KIAA0020 |
| Specificity | This antibody detects endogenous levels of PUF-A, KIAA0020 at Human, Mouse, Rat |
Additional Info
| Function | Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells. |
| Protein Name | Pumilio Homolog 3Hbv X-Transactivated Gene 5 ProteinHbv Xag-Transactivated Protein 5Minor Histocompatibility Antigen Ha-8Hla-Ha8 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusNucleoplasmChromosomeLocalizes Predominantly In The Nucleolus With Minor Punctate Signals In The Nucleoplasm |
| Alternative Antibody Names | Anti-Pumilio Homolog 3 antibodyAnti-Hbv X-Transactivated Gene 5 Protein antibodyAnti-Hbv Xag-Transactivated Protein 5 antibodyAnti-Minor Histocompatibility Antigen Ha-8 antibodyAnti-Hla-Ha8 antibodyAnti-PUM3 antibodyAnti-cPERP-C antibodyAnti-KIAA0020 antibodyAnti-PUF-A antibodyAnti-XTP5 antibody |
Information sourced from Uniprot.org