| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Receptor-type tyrosine-protein phosphatase R (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTPRR |
| Gene ID: |
5801 |
| Uniprot ID: |
PTPRR_HUMAN |
| Immunogen Region: |
N-Term |
| Specificity: |
This antibody detects endogenous levels of PTPRR at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human N-ternal PTPRR |
| Function | Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase RR-Ptp-RCh-1ptpaseNc-Ptpcom1Protein-Tyrosine Phosphatase Pcptp1 |
| Cellular Localisation | SecretedIsoform Alpha: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Delta: CytoplasmPerinuclear RegionLocates To The Perinuclear Areas Within The CytoplasmIsoform Gamma: Cytoplasm |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase R antibodyAnti-R-Ptp-R antibodyAnti-Ch-1ptpase antibodyAnti-Nc-Ptpcom1 antibodyAnti-Protein-Tyrosine Phosphatase Pcptp1 antibodyAnti-PTPRR antibodyAnti-ECPTP antibodyAnti-PTPRQ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
