Anti-PTPRO antibody (30-300) (STJ29038)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PTPRO (30-300) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTPRO |
| Gene ID | 5800 |
| Uniprot ID | PTPRO_HUMAN |
| Immunogen Region | 30-300 |
| Immunogen Sequence | FHVTVQDDNNIVVSLEASDV ISPASVYVVKITGESKNYFF EFEEFNSTLPPPVIFKASYH GLYYIITLVVVNGNVVTKPS RSITVLTKPLPVTSVSIYDY KPSPETGVLFEIHYPEKYNV FTRVNISYWEGKDFRTMLYK DFFKGKTVFNHWLPGMCYSN ITFQLVSEATFNKSTLVEYS GVSHEPKQHRTAPYPPQNIS VRIVNLNKNNWEEQSGNFPE ESFMRSQDTIGKEKLFHFT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human PTPRO (NP_109592.1). |
Additional Info
| Tissue Specificity | Glomerulus of kidney. Also detected in brain, lung and placenta. |
| Function | Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase OR-Ptp-OGlomerular Epithelial Protein 1Protein Tyrosine Phosphatase U2Ptp-U2Ptpase U2 |
| Database Links | Reactome: R-HSA-9034015 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase O antibodyAnti-R-Ptp-O antibodyAnti-Glomerular Epithelial Protein 1 antibodyAnti-Protein Tyrosine Phosphatase U2 antibodyAnti-Ptp-U2 antibodyAnti-Ptpase U2 antibodyAnti-PTPRO antibodyAnti-GLEPP1 antibodyAnti-PTPU2 antibody |
Information sourced from Uniprot.org