Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PTPRD |
Gene ID: | 5789 |
Uniprot ID: | PTPRD_HUMAN |
Immunogen Region: | 1100-1265 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1265 of human PTPRD (NP_002830.1). |
Immunogen Sequence: | TAKTAPDVLRTKPAFIGKTN LDGMITVQLPEVPANENIKG YYIIIVPLKKSRGKFIKPWE SPDEMELDELLKEISRKRRS IRYGREVELKPYIAAHFDVL PTEFTLGDDKHYGGFTNKQL QSGQEYVFFVLAVMEHAESK MYATSPYSDPVVSMDLDPQP ITDEEE |
Post Translational Modifications | A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization. |
Function | Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2. |
Protein Name | Receptor-Type Tyrosine-Protein Phosphatase DeltaProtein-Tyrosine Phosphatase DeltaR-Ptp-Delta |
Database Links | Reactome: R-HSA-388844Reactome: R-HSA-8849932 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase Delta antibodyAnti-Protein-Tyrosine Phosphatase Delta antibodyAnti-R-Ptp-Delta antibodyAnti-PTPRD antibody |
Information sourced from Uniprot.org