Anti-PTPRD antibody (1100-1265) (STJ118159)

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STJ118159
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTPRD
Gene ID: 5789
Uniprot ID: PTPRD_HUMAN
Immunogen Region: 1100-1265
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1265 of human PTPRD (NP_002830.1).
Immunogen Sequence: TAKTAPDVLRTKPAFIGKTN LDGMITVQLPEVPANENIKG YYIIIVPLKKSRGKFIKPWE SPDEMELDELLKEISRKRRS IRYGREVELKPYIAAHFDVL PTEFTLGDDKHYGGFTNKQL QSGQEYVFFVLAVMEHAESK MYATSPYSDPVVSMDLDPQP ITDEEE
Post Translational Modifications A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization.
Function Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase Delta
Protein-Tyrosine Phosphatase Delta
R-Ptp-Delta
Database Links Reactome: R-HSA-388844
Reactome: R-HSA-8849932
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase Delta antibody
Anti-Protein-Tyrosine Phosphatase Delta antibody
Anti-R-Ptp-Delta antibody
Anti-PTPRD antibody

Information sourced from Uniprot.org