| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Tyrosine-protein phosphatase non-receptor type 7 (95-145) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTPN7 |
| Gene ID: |
5778 |
| Uniprot ID: |
PTN7_HUMAN |
| Immunogen Region: |
95-145 |
| Specificity: |
This antibody detects endogenous levels of human PTN7 |
| Immunogen: |
Synthesized peptide derived from human PTN7 AA range: 95-145 |
| Post Translational Modifications | Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases. Oxidized at active site cysteine. Treatment with pervanadate (vanadate and H(2)O(2)) or with antigen enhanced oxidation of active site cysteine. |
| Function | Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction. |
| Protein Name | Tyrosine-Protein Phosphatase Non-Receptor Type 7Hematopoietic Protein-Tyrosine PhosphataseHeptpProtein-Tyrosine Phosphatase Lc-Ptp |
| Database Links | Reactome: R-HSA-5675221Reactome: R-HSA-9008059 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Tyrosine-Protein Phosphatase Non-Receptor Type 7 antibodyAnti-Hematopoietic Protein-Tyrosine Phosphatase antibodyAnti-Heptp antibodyAnti-Protein-Tyrosine Phosphatase Lc-Ptp antibodyAnti-PTPN7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
