| Post Translational Modifications | Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases. Oxidized at active site cysteine. Treatment with pervanadate (vanadate and H(2)O(2)) or with antigen enhanced oxidation of active site cysteine. |
| Function | Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction. |
| Protein Name | Tyrosine-Protein Phosphatase Non-Receptor Type 7Hematopoietic Protein-Tyrosine PhosphataseHeptpProtein-Tyrosine Phosphatase Lc-Ptp |
| Database Links | Reactome: R-HSA-5675221Reactome: R-HSA-9008059 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Tyrosine-Protein Phosphatase Non-Receptor Type 7 antibodyAnti-Hematopoietic Protein-Tyrosine Phosphatase antibodyAnti-Heptp antibodyAnti-Protein-Tyrosine Phosphatase Lc-Ptp antibodyAnti-PTPN7 antibody |
Information sourced from Uniprot.org
