| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tyrosine-protein phosphatase non-receptor type 13 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTPN13 |
| Gene ID: | 5783 |
| Uniprot ID: | PTN13_HUMAN |
| Specificity: | PTN13 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2. |
| Protein Name | Tyrosine-Protein Phosphatase Non-Receptor Type 13Fas-Associated Protein-Tyrosine Phosphatase 1Fap-1Ptp-BasProtein-Tyrosine Phosphatase 1ePtp-E1Hptpe1Protein-Tyrosine Phosphatase Ptpl1 |
| Database Links | Reactome: R-HSA-1660499Reactome: R-HSA-9008059Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273 |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCell ProjectionLamellipodiumColocalizes With F-ActinColocalizes With Pkn2 In Lamellipodia-Like StructureRegions Of Large Actin Turnover |
| Alternative Antibody Names | Anti-Tyrosine-Protein Phosphatase Non-Receptor Type 13 antibodyAnti-Fas-Associated Protein-Tyrosine Phosphatase 1 antibodyAnti-Fap-1 antibodyAnti-Ptp-Bas antibodyAnti-Protein-Tyrosine Phosphatase 1e antibodyAnti-Ptp-E1 antibodyAnti-Hptpe1 antibodyAnti-Protein-Tyrosine Phosphatase Ptpl1 antibodyAnti-PTPN13 antibodyAnti-PNP1 antibodyAnti-PTP1E antibodyAnti-PTPL1 antibody |
Information sourced from Uniprot.org
