| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Parathyroid hormone/parathyroid hormone-related peptide receptor (145-194 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTH1R |
| Gene ID: | 5745 |
| Uniprot ID: | PTH1R_HUMAN |
| Immunogen Region: | 145-194 aa |
| Specificity: | PTH/PTHrP-R Polyclonal Antibody detects endogenous levels of PTH/PTHrP-R protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PTHR1 at the amino acid range 145-194 |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. |
| Protein Name | Parathyroid Hormone/Parathyroid Hormone-Related Peptide ReceptorPth/Pthrp Type I ReceptorPth/Pthr ReceptorParathyroid Hormone 1 ReceptorPth1 Receptor |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor antibodyAnti-Pth/Pthrp Type I Receptor antibodyAnti-Pth/Pthr Receptor antibodyAnti-Parathyroid Hormone 1 Receptor antibodyAnti-Pth1 Receptor antibodyAnti-PTH1R antibodyAnti-PTHR antibodyAnti-PTHR1 antibody |
Information sourced from Uniprot.org