Name: Anti-PTH1R antibody (145-194 aa) (STJ95263)
SKU: STJ95263
Availability: InStock

Anti-PTH1R antibody (145-194 aa) (STJ95263)

SKU:

STJ95263

£48.00 - £252.00

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Rabbit polyclonal antibody anti-Parathyroid hormone/parathyroid hormone-related peptide receptor (145-194 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PTH1R
Gene ID:	5745
Uniprot ID:	PTH1R_HUMAN
Immunogen Region:	145-194 aa
Specificity:	PTH/PTHrP-R Polyclonal Antibody detects endogenous levels of PTH/PTHrP-R protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human PTHR1 at the amino acid range 145-194

Post Translational Modifications	N-glycosylated.
Function	G-protein-coupled receptor for parathyroid hormone (PTH) and for parathyroid hormone-related peptide (PTHLH). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). PTH1R is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. PTHLH dissociates from PTH1R more rapidly than PTH.as consequence, the cAMP response induced by PTHLH decays faster than the response induced by PTH.
Protein Name	Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor Pth/Pthrp Type I Receptor Pth/Pthr Receptor Parathyroid Hormone 1 Receptor Pth1 Receptor
Database Links	Reactome: R-HSA-373080 Reactome: R-HSA-418555
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor antibody Anti-Pth/Pthrp Type I Receptor antibody Anti-Pth/Pthr Receptor antibody Anti-Parathyroid Hormone 1 Receptor antibody Anti-Pth1 Receptor antibody Anti-PTH1R antibody Anti-PTHR antibody Anti-PTHR1 antibody

Information sourced from Uniprot.org

Anti-PTH1R antibody (145-194 aa) (STJ95263)

General Information

Model	Name	Host	Clonality	Reactivity	Application
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STJ95314	Anti-RBSN antibody (145-194 aa) (STJ95314)	Rabbit	Polyclonal	Human/Mouse	WB/ELISA/IHC
STJ95364	Anti-RANBP17 antibody (145-194 aa) (STJ95364)	Rabbit	Polyclonal	Human/Mouse	WB/IHC
STJ94967	Anti-PAX8 antibody (145-194 aa) (STJ94967)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC/IF/ELISA
STJ95699	Anti-SMAD3 antibody (145-194 aa) (STJ95699)	Rabbit	Polyclonal	Human/Mouse/Rat	IF/WB/IHC/ELISA