| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTGR3 |
| Gene ID: | 284273 |
| Uniprot ID: | PTGR3_HUMAN |
| Immunogen Region: | 33-371 |
| Specificity: | Recombinant Protein corresponding to a sequence within amino acids 33-371 of human PTGR3/ZADH2 (NP_787103.1). |
| Immunogen Sequence: | MQKLVVTRLSPNFREAVTLS RDCPVPLPGDGDLLVRNRFV GVNASDINYSAGRYDPSVKP PFDIGFEGIGEVVALGLSAS ARYTVGQAVAYMAPGSFAEY TVVPASIATPVPSVKPEYLT LLVSGTTAYISLKELGGLSE GKKVLVTAAAGGTGQFAMQL SKKAKCHVIGTCSSDEKSAF LKSLGCDRPINYKTEPVGTV LKQEYPEGVDVVYESVGGAM FDLAVDALATKGRLIVIGF |
| Function | Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. |
| Protein Name | Prostaglandin Reductase 3Prg-3Zinc-Binding Alcohol Dehydrogenase Domain-Containing Protein 2 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Prostaglandin Reductase 3 antibodyAnti-Prg-3 antibodyAnti-Zinc-Binding Alcohol Dehydrogenase Domain-Containing Protein 2 antibodyAnti-PTGR3 antibodyAnti-ZADH2 antibody |
Information sourced from Uniprot.org