| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PTGR2/ZADH1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 38kDa band observed in Pig Testis lysates (calculated MW of 38.4kDa according to Pig XP_001929109.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PTGR2 |
| Gene ID: | 145482 |
| Uniprot ID: | PTGR2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_689657.1 |
| Specificity: | Reported variants represent identical protein: NP_001139627.1, NP_689657.1, NP_001139626.1. |
| Immunogen Sequence: | PDNINEGQVQVRT |
| Function | Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. |
| Protein Name | Prostaglandin Reductase 2Prg-215-Oxoprostaglandin 13-ReductaseZinc-Binding Alcohol Dehydrogenase Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-2162123 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Prostaglandin Reductase 2 antibodyAnti-Prg-2 antibodyAnti-15-Oxoprostaglandin 13-Reductase antibodyAnti-Zinc-Binding Alcohol Dehydrogenase Domain-Containing Protein 1 antibodyAnti-PTGR2 antibodyAnti-ZADH1 antibody |
Information sourced from Uniprot.org