Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Prostaglandin E2 receptor EP4 subtype (321-370 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PTGER4 |
Gene ID: |
5734 |
Uniprot ID: |
PE2R4_HUMAN |
Immunogen Region: |
321-370 aa |
Specificity: |
EP4 Polyclonal Antibody detects endogenous levels of EP4 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human PE2R4 at the amino acid range 321-370 |
Post Translational Modifications | Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
Protein Name | Prostaglandin E2 Receptor Ep4 SubtypePge Receptor Ep4 SubtypePge2 Receptor Ep4 SubtypeProstanoid Ep4 Receptor |
Database Links | Reactome: R-HSA-391908Reactome: R-HSA-418555 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep4 Subtype antibodyAnti-Pge Receptor Ep4 Subtype antibodyAnti-Pge2 Receptor Ep4 Subtype antibodyAnti-Prostanoid Ep4 Receptor antibodyAnti-PTGER4 antibodyAnti-PTGER2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance