Anti-PTGER3 antibody (300-350) {FITC} (STJ500899)

SKU:
STJ500899-100

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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PTGER3 (300-350) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-0.6 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:250
IHC: 1:250
ICC: 1:250
IF: 1:250
CFM: 1:250
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PTGER3
Gene ID: 5733
Uniprot ID: PE2R3_HUMAN
Immunogen Region: 300-350
Immunogen: Synthetic peptide taken within amino acid region 300-350 on human Prostaglandin E2 receptor EP3 subtype.
Tissue Specificity Detected in kidney. Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium. Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration. Not required for normal kidney function, normal urine volume and osmolality.
Protein Name Prostaglandin E2 Receptor Ep3 Subtype
Pge Receptor Ep3 Subtype
Pge2 Receptor Ep3 Subtype
Pge2-R
Prostanoid Ep3 Receptor
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Prostaglandin E2 Receptor Ep3 Subtype antibody
Anti-Pge Receptor Ep3 Subtype antibody
Anti-Pge2 Receptor Ep3 Subtype antibody
Anti-Pge2-R antibody
Anti-Prostanoid Ep3 Receptor antibody
Anti-PTGER3 antibody

Information sourced from Uniprot.org

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