• Western blot analysis of the lysates from Jurkat cells using PE2R3 antibody.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PE2R3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from K562 cells, using PE2R3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of COS7 cells, using PE2R3 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-PTGER3 antibody (1-50 aa) (STJ92934)

SKU:
STJ92934

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Prostaglandin E2 receptor EP3 subtype (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGER3
Gene ID: 5733
Uniprot ID: PE2R3_HUMAN
Immunogen Region: 1-50 aa
Specificity: EP3 Polyclonal Antibody detects endogenous levels of EP3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PE2R3 at the amino acid range 1-50
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium. Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration. Not required for normal kidney function, normal urine volume and osmolality.
Protein Name Prostaglandin E2 Receptor Ep3 Subtype
Pge Receptor Ep3 Subtype
Pge2 Receptor Ep3 Subtype
Pge2-R
Prostanoid Ep3 Receptor
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Prostaglandin E2 Receptor Ep3 Subtype antibody
Anti-Pge Receptor Ep3 Subtype antibody
Anti-Pge2 Receptor Ep3 Subtype antibody
Anti-Pge2-R antibody
Anti-Prostanoid Ep3 Receptor antibody
Anti-PTGER3 antibody

Information sourced from Uniprot.org

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