Anti-PTGER1 antibody (300-400) (STJ114196)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PTGER1 (300-400) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTGER1 |
| Gene ID | 5731 |
| Uniprot ID | PE2R1_HUMAN |
| Immunogen Region | 300-400 |
| Immunogen Sequence | VGIMVVSCICWSPMLVLVAL AVGGWSSTSLQRPLFLAVRL ASWNQILDPWVYILLRQAVL RQLLRLLPPRAGAKGGPAGL GLTPSAWEASSLRSSRHSGL S |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PGE receptor EP1 (PGE receptor EP1 (PTGER1) ) (NP_000946.2). |
Additional Info
| Tissue Specificity | Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart. |
| Post Translational Modifications | Phosphorylated. |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
| Protein Name | Prostaglandin E2 Receptor Ep1 SubtypePge Receptor Ep1 SubtypePge2 Receptor Ep1 SubtypeProstanoid Ep1 Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep1 Subtype antibodyAnti-Pge Receptor Ep1 Subtype antibodyAnti-Pge2 Receptor Ep1 Subtype antibodyAnti-Prostanoid Ep1 Receptor antibodyAnti-PTGER1 antibody |
Information sourced from Uniprot.org