Western blot analysis of lysates from mouse pancreas, using PGE receptor EP1 (PTGER1) Rabbit polyclonal antibody (STJ114196) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-PTGER1 antibody (300-400) (STJ114196)

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STJ114196
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGER1
Gene ID: 5731
Uniprot ID: PE2R1_HUMAN
Immunogen Region: 300-400
Specificity: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PGE receptor EP1 (PGE receptor EP1 (PTGER1) ) (NP_000946.2).
Immunogen Sequence: VGIMVVSCICWSPMLVLVAL AVGGWSSTSLQRPLFLAVRL ASWNQILDPWVYILLRQAVL RQLLRLLPPRAGAKGGPAGL GLTPSAWEASSLRSSRHSGL S
Tissue Specificity Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.
Post Translational Modifications Phosphorylated.
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
Protein Name Prostaglandin E2 Receptor Ep1 Subtype
Pge Receptor Ep1 Subtype
Pge2 Receptor Ep1 Subtype
Prostanoid Ep1 Receptor
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Prostaglandin E2 Receptor Ep1 Subtype antibody
Anti-Pge Receptor Ep1 Subtype antibody
Anti-Pge2 Receptor Ep1 Subtype antibody
Anti-Prostanoid Ep1 Receptor antibody
Anti-PTGER1 antibody

Information sourced from Uniprot.org

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