![Anti-PTEN antibody [6H2.1] (STJ16101367)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/151876/346961/STJ16101367_1__87004.1681999192.jpg?c=1 "Anti-PTEN antibody [6H2.1] (STJ16101367)")
![Anti-PTEN antibody [6H2.1] (STJ16101367)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/151876/346961/STJ16101367_1__87004.1681999192.jpg?c=1 "Anti-PTEN antibody [6H2.1] (STJ16101367)")
Anti-PTEN antibody [6H2.1] (STJ16101367)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenC-terminal 100 aa of PTEN
General Information
| Short Description | Mouse monoclonal anti-PTEN for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 6H2.1 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Dilution Range | IHC-P 1:50-1:100 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | C-terminal 100 aa of PTEN |
Additional Info
| Background | PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers. Positive control tissue Breast, Renal Cell and Prostate carcinomas |
Information sourced from Uniprot.org