Anti-PTCHD1 antibody (Internal) (STJ72403)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-PTCHD1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 100kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 101kDa according to NP_775766.2). Recommended concentration: 0.5-2µg/ml.An additional band of unknown |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PTCHD1 |
| Gene ID | 139411 |
| Uniprot ID | PTHD1_HUMAN |
| Accession Number | NP_775766.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | DFQKTSRVSER |
Additional Info
| Function | Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. Can bind cholesterol in vitro. |
| Protein Name | Patched Domain-Containing Protein 1 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritic Spine |
| Alternative Antibody Names | Anti-Patched Domain-Containing Protein 1 antibodyAnti-PTCHD1 antibody |
Information sourced from Uniprot.org