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Anti-PSMC1 antibody (77-440) (STJ118158)

Western blot analysis of various lysates using PSMC1 Rabbit polyclonal antibody (STJ118158) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PSMC1 antibody (77-440) (STJ118158)

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STJ118158

£112.50 - £522.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-PSMC1 (77-440) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PSMC1
Gene ID:	5700
Uniprot ID:	PRS4_HUMAN
Immunogen Region:	77-440
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 77-440 of human PSMC1 (NP_002793.2).
Immunogen Sequence:	EFIRNQEQMKPLEEKQEEER SKVDDLRGTPMSVGTLEEII DDNHAIVSTSVGSEHYVSIL SFVDKDLLEPGCSVLLNHKV HAVIGVLMDDTDPLVTVMKV EKAPQETYADIGGLDNQIQE IKESVELPLTHPEYYEEMGI KPPKGVILYGPPGTGKTLLA KAVANQTSATFLRVVGSELI QKYLGDGPKLVRELFRVAEE HAPSIVFIDEIDAIGTKRYD SNSGGEREIQRTMLELLNQ

Function	Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC1 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Protein Name	26s Proteasome Regulatory Subunit 4 P26s4 26s Proteasome Aaa-Atpase Subunit Rpt2 Proteasome 26s Subunit Atpase 1
Database Links	Reactome: R-HSA-1169091 Reactome: R-HSA-1234176 Reactome: R-HSA-1236974 Reactome: R-HSA-1236978 Reactome: R-HSA-174084 Reactome: R-HSA-174113 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-180534 Reactome: R-HSA-180585 Reactome: R-HSA-187577 Reactome: R-HSA-195253 Reactome: R-HSA-202424 Reactome: R-HSA-211733 Reactome: R-HSA-2467813 Reactome: R-HSA-2871837 Reactome: R-HSA-349425 Reactome: R-HSA-350562 Reactome: R-HSA-382556 Reactome: R-HSA-450408 Reactome: R-HSA-4608870 Reactome: R-HSA-4641257 Reactome: R-HSA-4641258 Reactome: R-HSA-532668 Reactome: R-HSA-5358346 Reactome: R-HSA-5362768 Reactome: R-HSA-5607761 Reactome: R-HSA-5607764 Reactome: R-HSA-5610780 Reactome: R-HSA-5610783 Reactome: R-HSA-5610785 Reactome: R-HSA-5632684 Reactome: R-HSA-5658442 Reactome: R-HSA-5668541 Reactome: R-HSA-5676590 Reactome: R-HSA-5678895 Reactome: R-HSA-5687128 Reactome: R-HSA-5689603 Reactome: R-HSA-5689880 Reactome: R-HSA-68867 Reactome: R-HSA-68949 Reactome: R-HSA-69017 Reactome: R-HSA-69481 Reactome: R-HSA-69601 Reactome: R-HSA-75815 Reactome: R-HSA-8852276 Reactome: R-HSA-8854050 Reactome: R-HSA-8939236 Reactome: R-HSA-8939902 Reactome: R-HSA-8941858 Reactome: R-HSA-8948751 Reactome: R-HSA-8951664 Reactome: R-HSA-9010553 Reactome: R-HSA-9020702 Reactome: R-HSA-9604323 Reactome: R-HSA-9755511 Reactome: R-HSA-9762114 Reactome: R-HSA-9824272 Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Nucleus Membrane Lipid-Anchor
Alternative Antibody Names	Anti-26s Proteasome Regulatory Subunit 4 antibody Anti-P26s4 antibody Anti-26s Proteasome Aaa-Atpase Subunit Rpt2 antibody Anti-Proteasome 26s Subunit Atpase 1 antibody Anti-PSMC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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