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Anti-PSIP1 nanobody [SAA1182] (STJN000050)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Pc4 And Sfrs1-Interacting Protein is suitable for use in ELISA and SPR research applications. |
| Applications | ELISA/SPR |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1182 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | PSIP1 |
| Gene ID | 11168 |
| Uniprot ID | PSIP1_HUMAN |
Additional Info
| Post Translational Modifications | Citrullinated by PADI4. |
| Function | Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. |
| Protein Name | Pc4 And Sfrs1-Interacting ProteinCll-Associated Antigen Kw-7Dense Fine Speckles 70 Kda ProteinDfs 70Lens Epithelium-Derived Growth FactorTranscriptional Coactivator P75/P52 |
| Database Links | Reactome: R-HSA-162592Reactome: R-HSA-164843Reactome: R-HSA-175567Reactome: R-HSA-177539Reactome: R-HSA-180689Reactome: R-HSA-180910Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusRemains Chromatin-Associated Throughout The Cell Cycle |
| Alternative Nanobody Names | Anti-Pc4 And Sfrs1-Interacting Protein nanobodyAnti-Cll-Associated Antigen Kw-7 nanobodyAnti-Dense Fine Speckles 70 Kda Protein nanobodyAnti-Dfs 70 nanobodyAnti-Lens Epithelium-Derived Growth Factor nanobodyAnti-Transcriptional Coactivator P75/P52 nanobodyAnti-PSIP1 nanobodyAnti-DFS70 nanobodyAnti-LEDGF nanobodyAnti-PSIP2 nanobody |
Information sourced from Uniprot.org