| Host: | Goat |
| Applications: | Pep-ELISA/IF/FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PSCA (27-40) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Preliminary testing showed a band at <15kDa in Human Colon lysate at a concentration of 2ug/ml (calculated Mwt.of 12.9kDa according to NP_005663.2). Primary incubation 1 hour at room te |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PSCA |
| Gene ID: | 8000 |
| Uniprot ID: | PSCA_HUMAN |
| Immunogen Region: | 27-40 |
| Accession Number: | NP_005663.1 |
| Immunogen Sequence: | KAQVSNEDCLQVEN |
| Post Translational Modifications | N-glycosylated. |
| Function | May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs. |
| Protein Name | Prostate Stem Cell Antigen |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Prostate Stem Cell Antigen antibodyAnti-PSCA antibodyAnti-UNQ206 antibodyAnti-PRO232 antibody |
Information sourced from Uniprot.org