| Host: | Mouse |
| Applications: | IHC/WB/IF/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Puromycin-Sensitive Aminopeptidase (100-200) is suitable for use in Immunohistochemistry, Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT114 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2bk |
| Formulation: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification: | Protein G |
| Dilution Range: | IHC 1:200-1000WB 1:500-2000IF 1:100-500ELISA 1:1000-5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPEPPS |
| Gene ID: | 9520 |
| Uniprot ID: | PSA_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | The antibody can specifically recognize human PSA protein. |
| Immunogen: | Synthesized peptide derived from human Prostate-Specific Antigen (PSA) AA range: 100-200 |
| Function | Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. |
| Protein Name | Puromycin-Sensitive AminopeptidasePsaCytosol Alanyl AminopeptidaseAap-S |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Puromycin-Sensitive Aminopeptidase antibodyAnti-Psa antibodyAnti-Cytosol Alanyl Aminopeptidase antibodyAnti-Aap-S antibodyAnti-NPEPPS antibodyAnti-PSA antibody |
Information sourced from Uniprot.org
