Anti-PRXL2A antibody (STJA0008884)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C10orf58
General Information
| Short Description | Rabbit polyclonal anti-Peroxiredoxin-like 2A for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRXL2A |
| Gene ID | 84293 |
| Uniprot ID | PXL2A_HUMAN |
| Immunogen | Synthesized peptide derived from human C10orf58 |
| Specificity | This antibody detects endogenous levels of C10orf58 at Human, Mouse, Rat |
Additional Info
| Function | Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway. |
| Protein Name | Peroxiredoxin-Like 2aPeroxiredoxin-Like 2 Activated In M-Csf Stimulated MonocytesProtein PammRedox-Regulatory Protein Fam213a |
| Database Links | |
| Cellular Localisation | CytoplasmSecretedSecreted From Mature Adipocytes But Not From Preadipocytes |
| Alternative Antibody Names | Anti-Peroxiredoxin-Like 2a antibodyAnti-Peroxiredoxin-Like 2 Activated In M-Csf Stimulated Monocytes antibodyAnti-Protein Pamm antibodyAnti-Redox-Regulatory Protein Fam213a antibodyAnti-PRXL2A antibodyAnti-C10orf58 antibodyAnti-FAM213A antibodyAnti-PAMM antibodyAnti-PRO2290 antibodyAnti-PSEC0139 antibodyAnti-UNQ611 antibodyAnti-PRO1198 antibody |
Information sourced from Uniprot.org