| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Exopolyphosphatase PRUNE1 (48-98 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRUNE1 |
| Gene ID: | 58497 |
| Uniprot ID: | PRUN1_HUMAN |
| Immunogen Region: | 48-98 aa |
| Specificity: | This antibody detects endogenous levels of human PRUNE |
| Immunogen: | Synthesized peptide derived from the human PRUNE at the amino acid range 48-98 |
| Function | Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis. Involved in the regulation of microtubule polymerization. |
| Protein Name | Exopolyphosphatase Prune1Drosophila-Related Expressed Sequence 17Dres-17Dres17Htcd37Protein Prune Homolog 1Hprune |
| Cellular Localisation | CytoplasmNucleusCell JunctionFocal AdhesionIn Some Transfected Cells A Nuclear Staining Is Also Observed |
| Alternative Antibody Names | Anti-Exopolyphosphatase Prune1 antibodyAnti-Drosophila-Related Expressed Sequence 17 antibodyAnti-Dres-17 antibodyAnti-Dres17 antibodyAnti-Htcd37 antibodyAnti-Protein Prune Homolog 1 antibodyAnti-Hprune antibodyAnti-PRUNE1 antibodyAnti-PRUNE antibody |
Information sourced from Uniprot.org