| Short Description : | Rabbit polyclonal anti-Proline-rich protein 5-like for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRR5L |
| Gene ID: | 79899 |
| Uniprot ID: | PRR5L_HUMAN |
| Immunogen: | Synthesized peptide derived from human FLJ14213 |
| Specificity: | This antibody detects endogenous levels of FLJ14213 at Human, Mouse, Rat |
| Function | Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton. Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration. Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress. Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress. |
| Protein Name | Proline-Rich Protein 5-LikeProtein Observed With Rictor-2Protor-2 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Proline-Rich Protein 5-Like antibodyAnti-Protein Observed With Rictor-2 antibodyAnti-Protor-2 antibodyAnti-PRR5L antibodyAnti-PROTOR2 antibody |
Information sourced from Uniprot.org
