Anti-PRPF31 antibody (380-393 aa) [R01-7F1] (STJA0012670)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human PRPF31
General Information
| Short Description | Rabbit monoclonal anti-PRPF31 (380-393 aa) for use in WB, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-7F1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PRPF31 |
| Gene ID | 26121 |
| Uniprot ID | PRP31_HUMAN |
| Immunogen | A synthetic peptide of human PRPF31 |
| Immunogen Region | 380-393 aa |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | Phosphorylated by PRP4K during spliceosome assembly. |
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. |
| Protein Name | U4/U6 Small Nuclear Ribonucleoprotein Prp31Pre-Mrna-Processing Factor 31Serologically Defined Breast Cancer Antigen Ny-Br-99U4/U6 Snrnp 61 Kda ProteinProtein 61kHprp31 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleus SpeckleCajal BodyPredominantly Found In Speckles And In Cajal Bodies |
| Alternative Antibody Names | Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp31 antibodyAnti-Pre-Mrna-Processing Factor 31 antibodyAnti-Serologically Defined Breast Cancer Antigen Ny-Br-99 antibodyAnti-U4/U6 Snrnp 61 Kda Protein antibodyAnti-Protein 61k antibodyAnti-Hprp31 antibodyAnti-PRPF31 antibodyAnti-PRP31 antibody |
Information sourced from Uniprot.org