Anti-Progesterone Receptor antibody [ZR4] (STJ16101837)

SKU:
STJ16101837-1

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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Progesterone Receptor is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZR4
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tissue culture supernatant with 0.2% BSA and 15mM sodium azide
Purification: Concentrate
Dilution Range: IHC-P 1:200-1:400
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Recombinant protein encoding human progesterone receptor 412-526 aa
Background The progesterone receptor (PgR) is an estrogen regulated protein. It has been proposed that expression of PgR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies. Pretreatment: Heat induced epitope retrieval in 10 mM citrate buffer, pH6.0 for 20 minutes is required for IHC staining on formalin-fixed, paraffin embedded tissue sections. Note: Dilution of the antibody in 10% normal goat serum followed by a goat anti-rabbit secondary antibody-based detection is recommended. Control tisse Breast, breast ducatl carcinoma. Staining Nuclear

Information sourced from Uniprot.org

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