Anti-PRM2 antibody (STJA0006963)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PRM2
General Information
| Short Description | Rabbit polyclonal anti-Protamine-2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRM2 |
| Gene ID | 5620 |
| Uniprot ID | PRM2_HUMAN |
| Immunogen | Synthesized peptide derived from human PRM2 |
| Specificity | This antibody detects endogenous levels of PRM2 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Proteolytic processing into mature chains is required for histone eviction during spermatogenesis. Transition proteins (TNP1 and TNP2) are required for processing. |
| Function | Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. |
| Protein Name | Protamine-2Sperm Histone P2Sperm Protamine P2 Cleaved Into - Basic Nuclear Protein Hpi1 - Basic Nuclear Protein Hpi2 - Basic Nuclear Protein Hps1 - Basic Nuclear Protein Hps2 - Sperm Histone Hp4Sperm Protamine P4 - Sperm Histone Hp2Sperm Protamine P2P2' - Sperm Histone Hp3P2''Sperm Protamine P3 |
| Database Links | Reactome: R-HSA-9821993 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Protamine-2 antibodyAnti-Sperm Histone P2 antibodyAnti-Sperm Protamine P2 Cleaved Into - Basic Nuclear Protein Hpi1 - Basic Nuclear Protein Hpi2 - Basic Nuclear Protein Hps1 - Basic Nuclear Protein Hps2 - Sperm Histone Hp4 antibodyAnti-Sperm Protamine P4 - Sperm Histone Hp2 antibodyAnti-Sperm Protamine P2 antibodyAnti-P2' - Sperm Histone Hp3 antibodyAnti-P2'' antibodyAnti-Sperm Protamine P3 antibodyAnti-PRM2 antibody |
Information sourced from Uniprot.org